Set on the majestic hillside of Colle Ramole, just minutes from Porta Romana — the southernmost gateway into Florence — Dimora Ghirlandaio is one of the most historically extraordinary luxury villa rentals in Tuscany. The story begins in the mid-fourteenth century, when the Bigordi family left Florence to found a new homestead on these hills overlooking the Duomo. From this lineage came Domenico Ghirlandaio, descended from crown makers to the Florentine elite including the Medici family, and one of the most celebrated painters of the Quattrocento. Together with his son Ridolfo, he gave his name to what is now this elegantly restored borgo — a private sanctuary steeped in Renaissance history and sleeping up to 40 guests. Dimora Ghirlandaio is unlike any other villa rental near Florence. The estate comprises five individual villas, each with two to five bedrooms, a fireside living area, and a fully equipped kitchen, alongside two guesthouses each with their own private suite. All furnishings and finishings beautifully reflect local Florentine craftsmanship, and the manicured grounds are as impressive as the interiors — two swimming pools, including one of exceptional size, a poolside bar, a spa and treatment room, a restaurant, and a children's play area ensure that every guest, of every age, is perfectly catered for. A grass lawn helipad completes a picture of truly extraordinary hospitality. With a full five-star hotel-style staff and an in-house concierge on hand throughout every stay, the level of service here is seamless and deeply personal. Whether you are gathering a large family, hosting a milestone celebration, or looking for an exclusive private event venue near Florence, Dimora Ghirlandaio offers something that no hotel can match — the feeling of having one of Tuscany's most magnificent historic estates entirely to yourself. Available year-round, this is a Florence villa rental for those who want it all: history, beauty, space, and service of the very highest order.